In a healthy adult, there are 1011 to 1014 microbes colonizing the intestine, the intestinal microbiota is recognized to play pivotal roles in maintaining human health, and it is involved in many pathogenesis procedures. While the springing of sequencing technologies has contributed hugely to the profiling of microbial communities, many oligonucleotide microarrays have also been developed for this purpose. DNA microarray (also known as gene chip) is one such technology that a series of sequences or genes are orderly arranged in microarray to detect target DNAs or RNAs (most commonly as cDNA). The basic principle of DNA microarray is nucleic acid hybridization, the location and sequence of each spot of the slide are recorded and compared to get the needed information. This technique enables researchers to investigate and analyze the expression of thousands of genes in a single reaction and address issues more straightforwardly in both prokaryotic and eukaryotic cells.
Creative Proteomics assists researchers in developing customized microarray targeted at intestinal microbe genes of interest – For instance, genome arrays could be constructed using known and studied genomic DNA to monitor community composition; functional gene arrays could focus on enzymes encoding genes that are involved in various biochemical processes and benefit the studies on physiological changes in microbial communities; phylogenetic oligonucleotide arrays are ideally suited for the analysis of microbial community composition structure and variance.
We dedicate to providing the highest level of service in gut microbiota research. We provide support for both preliminary and advanced data analysis. Our customized service will guarantee that we deliver high-quality data and reports to you, and even provide more creative ideas for your research. To find more about DNA microarray for your gut microbiota research, please feel free to contact us. We will arrange experienced scientists to provide you with professional advice and optional services according to your project.
For Research Use Only. Not for use in diagnostic procedures.