The human gastrointestinal tract is colonized by a dense population of microbes of bacteria, viruses and microbial eukaryotes and form the communities that are referred as the gut microbiota, which play a pivotal role in maintaining host homeostasis, while the dysbiosis of the gut microbiota would cause a series of health issues including but not limited to gastrointestinal diseases, metabolic disorders, autoimmune disorders, mental disorders, and cancers. In order to attenuate these diseases or decrease the likelihood of suffering from them, various attempts have been developed to target at the gut microbiota and work as potential treatment methods, and fecal microbial transplant (FMT) is a representative and promising therapy to restore a healthy microbiota, which has seen significant effectiveness in treating diseases such as Clostridioides difficile infection (CDI) and ulcerative colitis.
Fecal microbial transplant attracts a lot of attention as a possible option for gut microbiota editing in the recent decade, which is the process of transplantation of fecal microbes from a healthy donor into the intestinal tract of a diseased recipient, with the procedure generally falling into the preparation of material, donor selection and screening, and FMT administration. And researcher started to realize that this unique approach is not only effective in treating gastrointestinal diseases but diseases involved with other organs or systems.
Figure 1. The progress of using microbes to treat human diseases. (Zhang 2018)
Creative Proteomics is a preeminent corporation that specializes in multi-omics. Equipped with cutting-edge techniques and served by well-experienced scientists, we have extensive experience to assist you in the fecal microbial transplant research and provide abundant research solutions into every aspect from the fundamental mechanism studies to clinical application development, and assist you in analyzing the methodology, clinical decision, and features including safety and efficacy, to help you make decisive breakthroughs in fecal microbial transplant (FMT) research. Specifically, our research solutions could cover but not limited to the following aspect:
◆ Possible usage of FMT diseases
◆ Microbiota profiling
◆ Model animal experiments
◆ Laboratory preparation of FMT
◆ Selective microbiota transplantation
◆ Suitable dosage forms
◆ Delivering ways
◆ Therapeutic schemes & Precision medicine development
◆ Safety and quality assessment
Creative Proteomics dedicates to providing the highest level of solutions in gut microbiota research. We will offer the most suitable strategies according to your sample and research purpose. Our specialty covers the full range of multi-omics including metagenomics, metatranscriptomics, metaproteomics, and metabolomics, coupled with powerful bioinformatics platforms, and other practical tools and resources, we provide the most comprehensive gut microbiota research solutions you will ever get. To find out more solutions for fecal microbial transplant research, please feel free to contact us.
1. Zhang F; et al. Microbiota transplantation: concept, methodology and strategy for its modernization. Protein & cell. 2018, 9(5): 462-73.
For Research Use Only. Not for use in diagnostic procedures.