A biomarker is anything that can be used as a measurable indicator of various physiological states or conditions, including normal biological processes, pathogenic processes, or pharmacologic responses to a therapeutic intervention. The gastrointestinal tract harbors a complex microbial ecosystem that performs numerous functions to the homeostasis of its host. Extensive studies have revealed that the composition and function of the gut microbiota vary in individuals of different factors such as diet, sex, age, geographical location, health condition, and genetics and thus may provide valid biomarkers in the gut microbiota-host interaction and can potentially be used in disease prediction, diagnosis, and treatment. The gut microbiota structure, as well as gut microbe-derived metabolites, can work as valid biomarkers, and the discovery of these biomarkers can be applied in manifold scientific fields.
Creative Proteomics is a preeminent corporation that specializes in multi-omics. Equipped with cutting-edge techniques and served by well-experienced scientists, we have extensive experience dealing with all kinds of difficulties you may have encountered in your research. As the microbiota biomarker research is under rapid expansion owing to the great advances of multi-omics technologies and sources, we will provide powerful tools and the most valid solutions to support your gut microbiota and biomarkers research, highlighting the significant information that gut microbiota biomarkers could offer to shed light upon studies into physiological functions, essential metabolic pathways, pathogenesis, and clinical applications.
Our specialty covers the full range of multi-omics including metagenomics, metatranscriptomics, metaproteomics, and metabolomics, thus we can provide comprehensive biomarker evaluation from all of the genetic level, transcription level, expression level, and metabolic level, and help you identify specific biomarkers and discover single or multiple biomarkers that have not been clarified yet.
We offer a one-stop solution of complete streamline from biomarker discovery to validation assessment for both basic scientific research and clinical application development.
● Using multi-omics technologies and bioinformatics platforms to screen for various biomarkers such as biochemical and genetic markers.
Proof of Concep
● Identifying the specific characteristics of the biomarkers, which is essential for in situ validation.
● Allowing the development of the most adapted protocol for routine use of the biomarker.
Analytical Performances Validation
● Identifying specific characteristics of the candidate biomarker before developing a routine test, such as sensitivity, specificity, accuracy, reproducibility, and so on.
Analytical Performances Validation
● Optimizing the validated protocol for routine use, including analysis of the critical points by scanning the entire procedure to identify and control the potential risks.
Creative Proteomics dedicates to providing the highest level of solutions in gut microbiota research. We will offer the most suitable strategies according to your sample and research purpose. And we would be more than happy to assist your research into gut microbiota projects and promote the health and wellbeing of mankind. To find out more solutions for gut microbiota and biomarker discovery, please feel free to contact us.
For Research Use Only. Not for use in diagnostic procedures.