The advent of next-generation sequencing has transformed the field of molecular biology, and high throughput sequencing platforms are routinely used in phylogenomic and metagenomic studies. Though the sequencing while synthesizing a large number of amplified identical DNA strands mechanism of next-generation sequencing limits the read-length of the procedure to ensure accuracy and fidelity. Thus, long DNA molecules must be broken up into small segments, which could be a major limitation to eukaryote DNA sequencing for eukaryotic genomes contain many repetitive regions. By sequencing of single molecules directly, third-generation sequencing technologies have the capability to sequence much longer reads than next-generation sequencing, creating a renaissance in high-quality genome sequencing, allowing for unbiased, more specific identification and even greater taxonomic resolution than second-generation sequencing methodologies for gut microbiota studies.
Creative Proteomics provides state-of-the-art experimental procedures and algorithmic strategies of third-generation sequencing to support your research into gut microbiota.
Our third-generation sequencing services can be widely applied in metagenomic sequencing, genome resequencing, genome de novo sequencing, transcriptome studies, methylation detection, epigenomics studies, detection of disease-related variations, viral analysis, etc. We also offer services of an alliance of third-generation sequencing and next-generation sequencing to acquire even more precise results. Customized service will guarantee the high quality of your subject and provide more sparkling ideas for your research, so feel free to contact us to find out more about suitable schemes for your research.
For Research Use Only. Not for use in diagnostic procedures.